This paper was published in Poultry Science in 2025, resulted from a collaboration between Morningbio Co., Ltd. and
Department of Poultry Science at the University of Georgia.
- Effect of coated organic acids on growth performance, Clostridium perfringens colonization, gut integrity and immune response in broilers
challenged with subclinical necrotic enteritis
The study examined the dose-dependent effects of coated organic acid (COA) supplementation on broiler performance and
gut health under subclinical necrotic enteritis (NE) challenge.
A total of 420 broilers were assigned to five groups, including a non-challenged control and four NE-challenged groups receiving 0%, 0.1%, 0.2%, or 0.4% dietary COA.
The results showed that COA improved feed efficiency during the starter phase and significantly increased body weight and feed intake during the NE challenge period.
Dietary COA also reduced Clostridium perfringens colonization, gut permeability, and lesion scores.
Gene expression analysis revealed that dietary COA modulated the expression of tight junction-related genes and immune-related genes.
These findings highlight COA's potential as an effective nutritional intervention to mitigate NE-related intestinal damage and
support gut health and immune function in broilers.